chemical inhibits protein has role has role is conjugate base of inhibitor sulfonamide antineoplastic agent aminopyrimidine tyrosine kinase inhibitor indazoles angiogenesis modulating agent vascular endothelial growth factor receptor antagonist pazopanib(1+) pazopanib 437.520 PMID:22830347 PMID:22688250 C1=C(C(=CC(=C1)NC=2N=CC=C(N2)N(C=3C=CC=4C(C3)=NN(C4C)C)C)S(N)(=O)=O)C PMID:23088634 5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide PMID:22716487 0 A pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer. PMID:22679111 C21H23N7O2S PMID:22861374 Reaxys:11646488 PMID:22595799 PMID:22233389 Patent:WO2011058179 chebi_ontology PMID:22190407 PMID:22112314 PMID:23064954 PMID:22341567 PMID:22759480 Patent:WO2007143483 PMID:21766486 Reference: PMID: 32368441 pazopanib Patent:WO2011069053 PMID:23072642 pazopanibum InChI=1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25) PMID:21394443 Drug_Central:4118 437.16339 Wikipedia:Pazopanib LINCS:LSM-1114 CAS:444731-52-6 PMID:22984765 CUIHSIWYWATEQL-UHFFFAOYSA-N CHEBI:71219 PMID:22733110 PMID:22733795 PMID:22359392 PMID:23135778 Patent:WO2012106302 GW786034 PMID:22917595 Patent:WO2011150044 Patent:WO2006020564 PMID:21811833 PMID:22766517 Patent:WO2007064753 GW 78603 Patent:US2008293691 PMID:23054212 serine/threonine-protein kinase MARK2