chemical inhibits protein chemical induces protein chemical inhibits in vitro replication of virus has role has role has functional parent guanine 2-aminopurines propane-1,3-diols antiviral drug penciclovir Nc1nc2n(CCC(CO)CO)cnc2c(=O)[nH]1 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine PMID: 32275812; PMID: 32020029 C10H15N5O3 Patent:US5075445 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine PMID:3040998 Reaxys:4501039 InChI=1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18) 253.25780 DrugBank:DB00299 A member of the class of 2-aminopurines that is guanine in which the hydrogen at position 9 is substituted by a 4-hydroxy-3-(hydroxymethyl)but-1-yl group. An antiviral drug, it is administered topically for treatment of herpes labialis. A prodrug, famciclovir, is used for oral administration. PDBeChem:PE2 PCV 0 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine 253.11749 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1,9-dihydro-6H-purin-6-one CHEBI:44870 CHEBI:7956 HMDB:HMDB0014444 chebi_ontology KEGG:C07417 penciclovir penciclovirum Wikipedia:Penciclovir Drug_Central:2079 PE2 CAS:39809-25-1 https://www.drugbank.ca/drugs/DB00299 LINCS:LSM-5587 JNTOCHDNEULJHD-UHFFFAOYSA-N KEGG:D05407 SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 severe acute respiratory syndrome coronavirus 2 DNA polymerase catalytic subunit (Herpes simplex virus type 1 strain 17)