<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/CIDO?iri=http://purl.obolibrary.org/obo/CHEBI_7989"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="http://purl.obolibrary.org/obo/chebi/"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/inchi"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/charge"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/smiles"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/inchikey"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/monoisotopicmass"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasAlternativeId"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/formula"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/mass"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CIDO_0000119 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/CIDO_0000119">
        <rdfs:label xml:lang="en">chemical inhibits protein</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label>has role</rdfs:label>
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/has_role -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/has_role"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_140325 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_140325">
        <rdfs:label>secondary carboxamide</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35222 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35222">
        <rdfs:label>inhibitor</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_48545 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_48545">
        <rdfs:label>pentapeptide</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_76885 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_76885">
        <rdfs:label>EC 3.4.23.* (aspartic endopeptidase) inhibitor</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_76969 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_76969">
        <rdfs:label>bacterial metabolite</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_7989 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_7989">
        <rdfs:label>pepstatin A</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_140325"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_48545"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/CIDO_0000119"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000006025"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_76969"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_76885"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/has_role"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35222"/>
            </Restriction>
        </rdfs:subClassOf>
        <oboInOwl:hasDbXref>CAS:26305-03-3</oboInOwl:hasDbXref>
        <ns5:inchi>InChI=1S/C34H63N5O9/c1-17(2)12-23(37-33(47)31(21(9)10)39-34(48)30(20(7)8)38-27(42)14-19(5)6)25(40)15-28(43)35-22(11)32(46)36-24(13-18(3)4)26(41)16-29(44)45/h17-26,30-31,40-41H,12-16H2,1-11H3,(H,35,43)(H,36,46)(H,37,47)(H,38,42)(H,39,48)(H,44,45)/t22-,23-,24-,25-,26-,30-,31-/m0/s1</ns5:inchi>
        <oboInOwl:hasDbXref>PMID:31130231</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:26524537</oboInOwl:hasDbXref>
        <ns5:inchikey>FAXGPCHRFPCXOO-LXTPJMTPSA-N</ns5:inchikey>
        <oboInOwl:hasDbXref>Wikipedia:Pepstatin</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22890034</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>procidin S 735A</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:31718885</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>pepsin inhibitor S 735A</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>LINCS:LSM-2282</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31374272</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:7989</oboInOwl:id>
        <ns3:IAO_0000115>A pentapeptide isolated from Streptomyces testaceus. It is a potent inhibitor of aspartyl proteases.</ns3:IAO_0000115>
        <oboInOwl:hasDbXref>PMID:19401235</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PDBeChem:IHN</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16762607</oboInOwl:hasDbXref>
        <ns5:smiles>CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(C)C)[C@@H](O)CC(O)=O</ns5:smiles>
        <oboInOwl:hasDbXref>KEGG:D03818</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C00773</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>ahpatinin C</oboInOwl:hasRelatedSynonym>
        <ns5:formula>C34H63N5O9</ns5:formula>
        <oboInOwl:hasDbXref>PMID:30658511</oboInOwl:hasDbXref>
        <ns5:charge>0</ns5:charge>
        <oboInOwl:hasDbXref>PMID:16633575</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:43324</oboInOwl:hasAlternativeId>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>PMID:4600212</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:6115767</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18675276</oboInOwl:hasDbXref>
        <ns5:mass>685.904</ns5:mass>
        <oboInOwl:hasDbXref>PMID:30408092</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>pepstatinum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:22205353</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>N-(3-methylbutanoyl)-L-valyl-N-[(3S,4S)-1-{[(2S)-1-{[(2S,3S)-1-carboxy-2-hydroxy-5-methylhexan-3-yl]amino}-1-oxopropan-2-yl]amino}-3-hydroxy-6-methyl-1-oxoheptan-4-yl]-L-valinamide</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>Reaxys:2201362</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:21344392</oboInOwl:hasDbXref>
        <ns3:IAO_0000119>Reference: PMID: 32253787</ns3:IAO_0000119>
        <oboInOwl:hasDbXref>PMID:22804908</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>pepstatin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-methyl-4-[(2S)-3-methyl-2-[(2S)-3-methyl-2-(3-methylbutanamido)butanamido]butanamido]heptanamido]propanamido]-6-methylheptanoic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>KNApSAcK:C00018785</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22384266</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>pepstatina</oboInOwl:hasRelatedSynonym>
        <ns5:monoisotopicmass>685.46258</ns5:monoisotopicmass>
        <oboInOwl:hasRelatedSynonym>pepstatine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000006025 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000006025">
        <rdfs:label>cathepsin D</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



