chemical inhibits protein has role has role ferroptosis inhibitor geroprotector pyridines antidepressant hypoglycemic agent aromatic ether xenobiotic insulin-sensitizing drug thiazolidinediones PPARgamma agonist EC 2.7.1.33 (pantothenate kinase) inhibitor cardioprotective agent pioglitazone Patent:EP193256 Drug_Central:2179 Reaxys:3595485 (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione PMID:34006325 356.11946 Chemspider:4663 PMID:27842070 CHEBI:8228 356.43978 CAS:111025-46-8 PMID:20797618 InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23) chebi_ontology Reference: PMID: 27510639 DrugBank:DB01132 PMID:12879407 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione PMID:33995271 PMID:33983968 0 LINCS:LSM-1592 PMID:34009030 Pioglitazone pioglitazone pioglitazonum A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity. PMID:14522601 PMID:33864097 HMDB:HMDB0015264 Wikipedia:Pioglitazone Beilstein:3595485 PMID:17628757 C19H20N2O3S HYAFETHFCAUJAY-UHFFFAOYSA-N Patent:US4687777 CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1 KEGG:D08378 PMID:33798599 pioglitazona PMID:18215232 KEGG:C07675 EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor CDGSH iron-sulfur domain-containing protein 1