is bearer of is_bearer_of chemical inhibits protein chemical has protein target as antagonist has role has role is conjugate base of anticoronaviral agent tertiary amine sedative local anaesthetic H1-receptor antagonist phenothiazines anti-allergic agent antiemetic antipruritic drug promethazine(1+) Promethazine promethazine chebi_ontology prometazina CAS:60-87-7 10-(2-Dimethylaminopropyl)phenothiazine Promethazine KEGG DRUG:D00494 Reaxys:88554 InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3 C17H20N2S KEGG:C07404 NIST Chemistry WebBook:60-87-7 284.13472 InChIKey=PWWVAXIEGOYWEE-UHFFFAOYSA-N A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety. HMDB:HMDB0015202 KEGG:D00494 InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3 LINCS:LSM-4440 https://www.drugbank.ca/drugs/DB01069 N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine CHEBI:8461 KEGG COMPOUND:60-87-7 A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety. proazamine Gmelin:337077 Patent:US2530451 Beilstein:88554 284.42018 (2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine Wikipedia:Promethazine DrugBank:DB01069 N-(2'-dimethylamino-2'-methyl)ethylphenothiazine 0 C17H20N2S CC(CN1c2ccccc2Sc2ccccc12)N(C)C 10-[2-(dimethylamino)propyl]phenothiazine ChemIDplus:60-87-7 promethazine Patent:US2607773 8745 Drug_Central:2286 CC(CN1c2ccccc2Sc2ccccc12)N(C)C KEGG COMPOUND:C07404 PWWVAXIEGOYWEE-UHFFFAOYSA-N N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine promethazinum function-inhibiting cytochrome P450 2D6 (CYP2D6) binding disposition cytochrome P450 isoenzyme 2D6 (CYP2D6) substrate disposition muscarinic acetylcholine receptor M2 (human) muscarinic acetylcholine receptor M4 (human) muscarinic acetylcholine receptor M5 (human) calmodulin-1 (human) muscarinic acetylcholine receptor M1 (human) D(2) dopamine receptor (human) muscarinic acetylcholine receptor M3 (human) histamine H2 receptor (human) histamine H1 receptor (human)