chemical has protein target as agonist chemical effective in vitro against virus has role has role benzoic acids hydrazines pyrazoles xenobiotic eltrombopag Drug_Central:4399 CC1=NN(C(=O)\C1=N/Nc1cccc(-c2cccc(c2)C(O)=O)c1O)c1ccc(C)c(C)c1 XDXWLKQMMKQXPV-QYQHSDTDSA-N 3'-{(2Z)-2-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazino}-2'-hydroxybiphenyl-3-carboxylic acid 3'-{(2Z)-2-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazinyl}-2'-hydroxy[1,1'-biphenyl]-3-carboxylic acid PMID:25170628 C25H22N4O4 0 PMID:25700916 Wikipedia:Eltrombopag PMID:24433306 PMID:25400215 CAS:496775-61-2 PMID:25063763 PMID: 32366720 https://www.drugbank.ca/drugs/DB06210 PMID:25578417 InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,26,30H,1-3H3,(H,32,33)/b27-22- 442.16411 CHEBI:85010 442.46660 A hydrazine in which each nitrogen atom is substituted, one by a 3'-carboxy-2-hydroxy[1,1'-biphenyl]-3-yl group and the other by a 1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene group. A small molecule agonist of the c-mpl (TpoR) receptor (the physiological target of the hormone thrombopoietin), it has been developed as a medication for conditions that lead to thrombocytopenia (abnormally low platelet counts). chebi_ontology thrombopoietin receptor agonist Severe acute respiratory syndrome-related coronavirus thrombopoietin receptor (human)