has_participant has participant TMPRSS2 cutting open S protein of SARS-CoV-2 A SARS-CoV-2 viral process in which after a SARS-CoV-2 virion attaches to a target cell, the cell's protease TMPRSS2 cuts open the spike protein of the virus, exposing a fusion peptide in the S2 subunit, and the host receptor ACE2. Oliver He https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102627/ https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2 SARS-CoV-2 viral process to host transmembrane protease serine 2 spike glycoprotein (SARS-CoV-2)