process has causal agent host response to SARS-CoV-2 infection cytokine storm response to SARS-CoV-2 infection https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194613/ Cytokine storm is considered to be one of the major causes of Acute respiratory distress syndrome (ARDS) and multiple-organ failure, which often occur rapidly and resulted in death of COVID-19 patients within a short time. Cytokine storm plays an important role in the process of disease aggravation. Ref: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194613/ interleukin-6 (human)