catalyzed by has input has output Ile(5)-angiotensin II (1-7) hydrolysis of angiotensin II into angiotensin (1-7) hydrolysis of angiotensin II into angiotensin (1-7) by ACE2 Oliver He A protein process where ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II (a vasoconstrictor peptide) into angiotensin (1–7) (a vasodilator). ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II and increasing Ang(1-7), making it a promising drug target for treating cardiovascular diseases. https://en.wikipedia.org/wiki/Angiotensin-converting_enzyme_2 protein processing angiotensin-converting enzyme 2 angiotensin II