chemical entity coronaviral amino acid variant A chemical entity that is an amino acid variant in a coronavirus proteome. Such an amino acid variant is defined as a substittion of amino acid residues. Such a variant is defined by comparing with the reference strain of the coronavirus. For example, D614G is a SARS-CoV-2 coronoviral amino acid variant that has the change from D to G at the position 614 compared with the reference Wuhan strain. Oliver He, Anthony Huffman coronaviral amino acid variant