has_participant has participant G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway G-protein coupled receptor signaling pathway coupled to IP3 second messenger G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) G protein signaling, coupled to IP3 second messenger (phospholipase C activating) G protein signalling, coupled to IP3 second messenger (phospholipase C activating) activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger G-protein signalling, coupled to IP3 second messenger (phospholipase C activating) This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) activity. phospholipase C-activating dopamine receptor signaling pathway biological_process phospholipase C-activating G-protein coupled receptor signaling pathway PLC-activating GPCR signaling pathway GO:0007200 A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase C (PLC) and a subsequent increase in the intracellular concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG). estrogen receptor (human) 5-hydroxytryptamine receptor 2A (human) 5-hydroxytryptamine receptor 2C (human) alpha-1A adrenergic receptor (human) histamine H1 receptor (human) alpha-1B adrenergic receptor (human) mu-type opioid receptor (human) delta-type opioid receptor (human) kappa-type opioid receptor (human) 5-hydroxytryptamine receptor 2B (human)