has_participant has participant regulation of phosphatidylinositol 3-kinase signaling regulation of phosphoinositide 3-kinase cascade regulation of PI3K cascade regulation of phosphatidylinositol 3-kinase cascade regulation of PI 3-kinase cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade. GO:0014066 biological_process regulation of intracellular signal transduction tyrosine-protein kinase Lck (human) tyrosine-protein kinase Fyn (human) fibroblast growth factor 2 (human) platelet-derived growth factor receptor beta (human) mast/stem cell growth factor receptor Kit (human) platelet-derived growth factor receptor alpha (human)