has_participant has participant response to organic cyclic compound response to estradiol response to estradiol stimulus GO:0032355 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. response to E2 stimulus biological_process response to lipid response to oxygen-containing compound estrogen receptor (human) annexin A1 (human) glutathione S-transferase P (human) platelet-derived growth factor receptor beta (human) sodium-dependent serotonin transporter (human) caspase-3 (human) signal transducer and activator of transcription 5B (human)