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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000057">
        <rdfs:label>has_participant</rdfs:label>
        <rdfs:label xml:lang="en">has participant</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/GO_0035094 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0035094">
        <rdfs:label>response to nicotine</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0042221"/>
        <rdfs:subClassOf>
            <Restriction>
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                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_P42574"/>
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        <ns3:IAO_0000115>Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.</ns3:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/GO_0042221 -->

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    <!-- http://purl.obolibrary.org/obo/PR_P14416 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_P14416">
        <rdfs:label>D(2) dopamine receptor (human)</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/PR_Q01959 -->

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        <rdfs:label>sodium-dependent dopamine transporter (human)</rdfs:label>
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