LPAR1/S1PR1-like lysophospholipid receptor lysophospholipid (S1P) receptor sphingosine 1-phosphate receptor 1-5 PIRSF:PIRSF501018 IUPHARfam:135 PR:000001673 protein An LPAR1/S1PR1-like lysophospholipid receptor that is a translation product of the human S1PR1, S1PR2, S1PR3, S1PR4, or S1PR5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues. Category=family.