lysophospholipid (S1P) receptor sphingosine 1-phosphate receptor 1 sphingosine 1-phosphate receptor Edg-1 EDG1 endothelial differentiation G-protein coupled receptor 1 PR:000001706 IUPHARobj:275 A lysophospholipid (S1P) receptor that is a translation product of the human S1PR1 gene or a 1:1 ortholog thereof. The receptor is specifically expressed in endothelial cells, and to a lesser extent, in vascular smooth muscle cells, fibroblasts, melanocytes, and cells of epithelioid origin. S1P receptor 1 Lpb1 lysophospholipid receptor B1 S1P1 protein S1PR1 S1P receptor Edg-1 CD363 CHEDG1 Category=gene.