chemical activates protein participates in transcription initiation from RNA polymerase II promoter signal transduction positive regulation of gene expression steroid hormone mediated signaling pathway nuclear receptor subfamily 1 group I member 2 Homo sapiens protein nuclear receptor subfamily 1 group I member 2 (human) steroid and xenobiotic receptor (human) SXR (human) hNR1I2 orphan nuclear receptor PXR (human) Reactome:R-HSA-3196156 DTO:00117497 protein orphan nuclear receptor PAR1 (human) Category=organism-gene. PR:O75469 pregnane X receptor (human) Reactome:R-HSA-3196164 UniProtKB:O75469 NR1I2 https://www.drugbank.ca/drugs/DB00503 PXR A nuclear receptor subfamily 1 group I member 2 that is encoded in the genome of human.