has part has characteristic develops from capable of mature basophil polymorphonuclear leucocyte CALOHA:TS-0688 mature basophil leucocyte BTO:0001026 Mature basophils are also capable of producing IL-3, IL-5, IL-6, IL-8, IL-13, IL-25, CCL22, tslp, vegf, and LTC4. mature basophil leukocyte polymorphonuclear leukocyte A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. basophil band form basophil histamine secreting cell histamine production involved in inflammatory response serotonin production involved in inflammatory response positive regulation of type 2 immune response nucleus blood circulation interleukin-13 production interleukin-4 production positive regulation of isotype switching to IgE isotypes lobed