part of part of directly develops from ependymal cell ependymal cell A neuroepithelial glial cell, derived from a radial glial cell originating from the neuroectoderm, lines the ventricles of the brain and the central canal of the spinal cord. This cell is characterized by the presence of cilia on its apical surface, which can be motile or non-motile. FMA:70550 BTO:0001724 ZFA:0009033 https://cellxgene.cziscience.com/cellguide/CL_0000065 ependymocyte Ependymal cells are ciliated neuroepithelial cells lining the ventricles of the brain and the central canal of the spinal cord, forming a single-layered epithelium, known as the ependyma. Together with astrocytes, microglial cells, and oligodendrocytes, they are one of the four main types of neuroglia found in the nervous system. Ependymal cells are equipped with multiple functions that support the brain and spinal cord. Key amongst these functions are the secretion, circulation, and absorption of cerebrospinal fluid, which cushions the brain, distributes neuroendocrine factors, and disposes of neural waste. The cilia on the apical surface of ependymal cells vigorously beat in a coordinated fashion to circulate the cerebrospinal fluid. Additionally, these cells may also function in aiding the migration of neuroblasts during brain development. Ependymal cells form a barrier between the cerebrospinal fluid and the adjacent nervous tissue in the central nervous system, which appears to be particularly important during development. In response to injury, ependymal cells have been observed to proliferate and have the potential to transform into astrocytes or oligodendrocytes, suggesting stem cell-like functions. (This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.) epithelial cell ciliated epithelial cell glial cell radial glial cell neurecto-epithelial cell ependyma