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     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
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     xmlns:dcterms="http://purl.org/dc/terms/"
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     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/cl#human_subset"/>
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    <!-- http://purl.obolibrary.org/obo/RO_0000053 -->

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        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#InverseFunctionalProperty"/>
        <rdfs:label xml:lang="en">has characteristic</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CL_0000000 -->

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        <rdfs:label>cell</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CL_0000412 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000412">
        <rdfs:label>polyploid cell</rdfs:label>
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        <rdfs:seeAlso>https://cellxgene.cziscience.com/cellguide/CL_0000412</rdfs:seeAlso>
        <ns4:IAO_0000115>A cell that contains more than two haploid sets of chromosomes.</ns4:IAO_0000115>
        <dcterms:description>A polyploid cell is a unique type of cell characterized by the possession of more than two sets of chromosomes. This is much higher than the typical diploid nature of other somatic cells. This cellular phenomenon known as polyploidy results from errors during cell division leading to the generation of non-standard polyploid cells, a property that is common to both plant and animal cells. These cells occur naturally and can also be formed through genetic manipulation.
Polyploid cells play a critical role in the overall growth and development of organisms. In plant cells, polyploidy often contributes to speciation and diversity. A notable characteristic of many plant species is their ability to tolerate polyploidy, a trait that often leads to increased cell size, altered gene expression, and may enhance the physiological and adaptive traits of a plant. In animals, polyploidy is less common but still plays a significant role in liver function and injury repair. Polyploidization in hepatocytes aids in maintaining genetic stability and also allows for cellular adaptation to liver injury.
Polyploid cells also play a potential role in cancer development. Some cancer cells are polyploid or aneuploid (having an abnormal number of chromosomes) indicating a relationship between chromosome status and cancer progression. Polyploidy in cancer cells may contribute to increased mutation rates, adaptation to adverse environments, and resistance to chemotherapy.  Overall, polyploid cells may lead to pathological conditions like cancer, however, many are part of normal healthy biological systems, playing an integral role in the diversity and evolution of life.

(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)</dcterms:description>
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    <!-- http://purl.obolibrary.org/obo/PATO_0001377 -->

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        <rdfs:label>polyploid</rdfs:label>
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