<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/CL?iri=http://purl.obolibrary.org/obo/CL_0001041"?>
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     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:cl="http://purl.obolibrary.org/obo/cl#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/cl#human_subset"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/cl#mouse_subset"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0002104 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002104">
        <rdfs:label xml:lang="en">has plasma membrane part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002215 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002215">
        <rdfs:label xml:lang="en">capable of</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CL_0000795 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000795">
        <rdfs:label>CD8-positive, alpha-beta regulatory T cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0001041 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0001041">
        <rdfs:label>CD8-positive, CXCR3-positive, alpha-beta regulatory T cell</rdfs:label>
        <equivalentClass>
            <Class>
                <intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000795"/>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002104"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000001207"/>
                    </Restriction>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002215"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0032613"/>
                    </Restriction>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002215"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0032689"/>
                    </Restriction>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002215"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042130"/>
                    </Restriction>
                </intersectionOf>
            </Class>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000795"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002215"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0042130"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002215"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0032689"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002104"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000001207"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002215"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0032613"/>
            </Restriction>
        </rdfs:subClassOf>
        <oboInOwl:hasExactSynonym>CD8+CXCR3+ T(reg)</oboInOwl:hasExactSynonym>
        <rdfs:comment>These cells may be the human equivalent of murine CD8-positive, CD122-positive alpha-beta regulatory T cell. They are also found in the CD45RA-negative and CD62L-positive fraction.</rdfs:comment>
        <oboInOwl:hasExactSynonym>CD8-positive, CXCR3-positive, alpha-beta regulatory T-lymphocyte</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>CD8+CXCR3+ T-cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>CD8+CXCR3+ T lymphocyte</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>CD8-positive, CXCR3-positive, Treg</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>CD8-positive, CXCR3-positive, alpha-beta regulatory T lymphocyte</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>CD8+CXCR3+ T cell</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>A CD8-positive alpha-beta-positive T cell with the phenotype CXCR3-positive and having suppressor function. They are capable of producing IL-10, suppressing proliferation, and suppressing IFN-gamma production.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>CD8-positive, CXCR3-positive, T(reg)</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>CD8+CXCR3+ Treg</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>CD8-positive, CXCR3-positive, alpha-beta regulatory T-cell</oboInOwl:hasExactSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/cl#human_subset"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/cl#mouse_subset"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0032613 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0032613">
        <rdfs:label>interleukin-10 production</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0032689 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0032689">
        <rdfs:label>negative regulation of type II interferon production</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0042130 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0042130">
        <rdfs:label>negative regulation of T cell proliferation</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001207 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000001207">
        <rdfs:label>C-X-C chemokine receptor type 3</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



