part of part of stromal cell stromal cell of ovary 2010-08-23T12:10:31Z https://cellxgene.cziscience.com/cellguide/CL_0002132 Stromal cells of the ovary, also known as ovarian stromal cells, form a significant portion of the ovarian tissue. They are non-epithelial cells that primarily make up the supportive or connective tissue—similar to the stroma of other organs—in the ovaries. These cells play vital roles in folliculogenesis, including in the activation of primordial follicles and in the differentiation of theca cells. They are crucial for maintaining the structure, function, and overall health of the ovaries. In addition to roles in hormone production and follicle maturation, stromal cells of the ovary play a role in ovarian aging and age-related diseases such as ovarian cancer. They participate in cell-to-cell communication with oocyte and other ovarian cell types through gap junctions and paracrine signaling and help maintain the ovarian microenvironment. (This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.) FMA:72299 A stomal cell of the ovary ovarian stromal cell ovary