part of part of adipocyte adipocyte of breast 2011-03-14T10:17:07Z breast adipocyte An adipocyte that is part of the breast. Adipocytes found in the subcutaneous adipose tissue of breast. The breast consists of three main components, the skin, the subcutaneous adipose tissue and the functional glandular tissue that comprises both parenchyma and stroma.[CALOHA] fat cell of breast https://cellxgene.cziscience.com/cellguide/CL_0002617 CALOHA:TS-2377 Adipocytes of the breast, commonly known as breast fat cells, serve crucial structural, protective, and metabolic roles. These specialized cells, ubiquitously found within the breast's adipose tissue, primarily contribute to the organ's overall shape and cushioning, providing physical support to surrounding structures. Adipocytes are highly active metabolically and play a key role in lipid homeostasis, acting as principal sites for energy storage and release. These cells store excess energy in the form of triglycerides during times of energy surplus, releasing it during periods of energy deficit as free fatty acids and glycerol into the bloodstream. Therefore, regulation of breast adipocytes' size and number is critical to maintain overall energy balance. Moreover, during lactation, these fat cells assist in providing lipid molecules necessary for the production of breast milk. Moreover, breast adipocytes notably function in the endocrine system, secreting a wide array of hormones, growth factors, and cytokines, collectively referred to as adipokines. While adipokines have a wide range of effects, some are believed to exert crucial influence on breast cancer physiology. Indeed, excessive adipose tissue, leading to a state of chronic low-grade inflammation, is associated with an increased risk of several types of cancer, including breast cancer. (This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.) breast