has soma location has soma location cardiac neuron https://github.com/obophenotype/cell-ontology/pull/1488 A neuron that has its soma in the heart. Cardiac neurons are a specialized type of neuron found within the heart tissue. They are the primary constituents of the intrinsic cardiac nervous system, also known as the cardiac plexus or intrinsic cardiac ganglia, which is responsible for the regulation of the heart's rhythmic contractions and overall functioning. This group of neurons is integral to the autonomic control of the heart and plays a crucial role in modulating cardiac activity, thereby playing an essential role in maintaining cardiovascular homeostasis. These neurons are responsible for both the sympathetic and parasympathetic regulation of the heart’s function. In terms of sympathetic control, cardiac neurons respond to the release of norepinephrine, which increases heart rate, strength of contractions, and blood pressure. Conversely, with regards to parasympathetic control, these neurons respond to the neurotransmitter acetylcholine, which decreases heart rate, blood pressure, and the strength of contractions. Thus, the balance between these sympathetic and parasympathetic inputs regulated by cardiac neurons is essential for normal heart function. Cardiac neurons also partake in the transmission of pain signals during conditions such as myocardial ischemia, contributing to the symptomatology of ischemic heart disease. Additionally, abnormal function or pathological alterations in these neurons could lead to various cardiac dysfunctions, including arrhythmias and heart failure. (This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.) https://cellxgene.cziscience.com/cellguide/CL_0010022 This term is used in 3 GO terms that were created as part of the heart development focus project. peripheral nervous system neuron heart