part of part of develops from goblet cell intestinal epithelial cell intestine goblet cell 2020-10-14T14:59:07Z intestinal goblet cell Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins. Human intestinal goblet cells secrete the MUC2 mucin, as well as a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3. transit amplifying cell of gut intestinal epithelium