part of part of stromal cell fasciacyte 2026-02-20T14:27:58Z Stecco et al. demonstrate that fasciacytes differ from classical fascial fibroblasts in morphology, location (small clusters at the interface between fibrous and loose fascial layers), marker profile (S-100A4 expression), and ECM output (HA-rich rather than collagen-rich). A mesenchymal stromal cell of the deep fascia (e.g., fascia lata) that is vimentin-positive, CD68-negative, and S-100A4-positive, organized in small clusters at the interface between fibrous fascial sublayers and loose connective tissue. It is specialized for hyaluronan-rich ECM biosynthesis, as evidenced by HAS2 mRNA expression, Alcian Blue staining, and anti-HABP immunoreactivity, and functions to regulate fascial gliding and viscoelasticity. deep fascia