Dogiel type II neuron intrinsic primary afferent neuron of myenteric plexus Dogiel type II neuron of myenteric plexus 2026-03-10T14:42:58Z An intrinsic primary afferent neuron of the myenteric plexus characterised by Dogiel type II morphology: a large, smooth, oval soma bearing multiple long axon-like processes that extend without branching until they reach their targets in both the myenteric and submucosal plexuses and the mucosa. The soma lacks the dendrites characteristic of Dogiel type I neurons and is larger in cross-sectional area than either motor neuron type. This neuron is immunopositive for choline acetyltransferase (ChAT) and immunonegative for neuronal nitric oxide synthase (NOS1). It exhibits AH-type electrophysiology, characterised by a prolonged afterhyperpolarization (AHP) following an action potential. Substance P (encoded by TAC1) expression has been reported in subsets across species. type II myenteric neuron multiaxonal myenteric sensory neuron GitHub Copilot AH-type myenteric neuron