part of part of fibroblast periductal fibroblast of salivary gland 2026-03-24T10:46:30Z immunofibroblast of salivary gland salivary gland fibroblast A fibroblast that is part of the stroma of a salivary gland, positioned in the periductal connective tissue surrounding the ductal system. This cell maintains the extracellular matrix framework around salivary gland ducts and participates in immunomodulatory signaling. In the context of Sjögren's syndrome, periductal fibroblasts respond to IL-13 stimulation by upregulating VCAM-1, PDPN, and ICAM-1, contributing to the formation of tertiary lymphoid structures (Nayar et al., 2019). saliva-secreting gland