has soma location has soma location glutamatergic neuron CA2 pyramidal cell 2026-05-26T13:30:22Z GitHub Copilot A hippocampal pyramidal neuron with soma located in the pyramidal layer of hippocampal area CA2 (Cembrowski et al., 2016; Sanchez-Aguilera et al., 2021). Distinguished from CA1 and CA3 pyramidal neurons by expression of Pcp4, Rgs14, and Amigo2 in rodents (San Antonio et al., 2014; Caruana et al., 2012), and by absence of the CA1 marker wolframin (Wfs1) (Evans et al., 2018). Receives strong LTP-competent input from entorhinal cortex at distal dendrites, while Schaffer collateral inputs to proximal dendrites are resistant to canonical LTP in wild-type animals (Chevaleyre & Siegelbaum, 2010). Required for social memory in mice (Hitti & Siegelbaum, 2014). pyramidal cell of CA2 CA2 pyramidal neuron hippocampal pyramidal neuron pyramidal layer of CA2