has soma location has soma location glutamatergic neuron CA1 pyramidal cell 2026-05-21T09:55:20Z GitHub Copilot pyramidal cell of CA1 https://github.com/obophenotype/cell-ontology/issues/3646 A hippocampal pyramidal neuron with soma located in the pyramidal layer of hippocampal area CA1 (Cembrowski et al., 2016; Müller & Remy, 2017), forming the dominant excitatory projection population of the CA1 subfield. As the primary output cell of Ammon's horn, it projects via the subiculum to entorhinal cortex and is capable of glutamate secretion as a neurotransmitter (Dale et al., 2015). In mouse, it is distinguished from CA2 and CA3 pyramidal neurons by soma position within the CA1 stratum pyramidale and by expression of wolframin (Wfs1), an endoplasmic reticulum-resident membrane protein enriched in deep-sublayer CA1 cells (Cembrowski et al., 2016). CA1 pyramidal neuron hippocampal pyramidal neuron pyramidal layer of CA1