part of part of has characterizing marker set NS forest marker set of bronchial goblet cell (Human lung). goblet cell bronchial epithelial cell tracheobronchial goblet cell bronchial goblet cell Bronchial goblet cells are a subset of goblet cells that are predominantly found in the respiratory tract, specifically within the bronchi and bronchioles. Named for their flask-like shape and their apparent similarity to a goblet, these cells contribute significantly to the maintenance of lung health and homeostasis. In humans, goblet cells comprise up to 25% of the bronchial epithelial columnar cells and are an integral part of the mucus-secreting system of the respiratory tract and are primarily responsible for the production and secretion of mucus. The mucus secreted by bronchial goblet cells serves as a protective layer over the delicate and sensitive structures of the bronchi. The mucus, an amalgamation of glycoproteins, lipids, and other substances, traps any inhaled dust, microorganisms, and pollutants, preventing them from reaching deeper lung tissues and causing potential damage. Additionally, the mucus secretion aids in moistening the airway surface, thereby facilitating effective gas exchange and maintaining the overall health of the respiratory tract. Bronchial goblet cells have an innate defense mechanism wherein they increase secretion of mucus in response to irritants, infection or inflammation in the airway. This strategy, however, if incessantly stimulated, can lead to airway obstruction and health complications like asthma and chronic obstructive pulmonary disease (COPD). (This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.) A goblet cell that is part of the epithelium of bronchus. The marker set PLCG2, ANKRD36C can identify the Human cell type bronchial goblet cell in the lung with a confidence of 0.55 (NS-Forest FBeta value). goblet cell of epithelium of bronchus FMA:263032 https://cellxgene.cziscience.com/cellguide/CL_1000312 Homo sapiens bronchus