part of part of glandular secretory epithelial cell glandular cell of the large intestine colon epithelial cell colon glandular cell https://cellxgene.cziscience.com/cellguide/CL_1001588 Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells. CALOHA:TS-1274 colon glandular cells Colon glandular cells are a specific type of epithelial cells that make up part of the lining of the colon. These cells are a specific subset of colon epithelial cells and are organized into structures called glands or crypts that are vertically oriented and are arrayed along the interior surface of the colon. The primary function of these cells is to facilitate absorption, secrete mucus and maintain the barrier within the colon. The function of absorption mainly involves the absorption of water from wastes moving through the digestive system, leading to the formation of solid stool. This role is vital in preventing dehydration and maintaining the balance of fluids in the body. Another significant function of the colon glandular cells lies in their ability to secrete mucus. The mucus forms a protective lining that prevents the direct contact of waste material with the cellular lining of the colon, protecting them from damage and reducing friction during waste movement. Additionally, colon glandular cells serve a crucial role in maintaining the colon's barrier. They protect the body from harmful substances and microorganisms present in the gut. Any disruption to these cells can lead to disorders such as inflammatory bowel disease, including ulcerative colitis and Crohn's disease. (This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.) colon