expresses expresses GABAergic neuron cerebral cortex neuron meis2 expressing cortical GABAergic cell The meis2 expressing cortical GABAergic cell is a unique and specialized type of neuron found within the complex architecture of the cerebral cortex. Specifically, these neurons originate from a region bordering the pallium and subpallium. Meis2 refers to the gene that codes for the Meis homeobox2 protein, which is a crucial transcription factor that regulates neural development. Most importantly, the GABAergic characteristic of these cells refers to their function in relation to the release of the neurotransmitter gamma-aminobutyric acid (GABA), which carries inhibitory signals to help maintain stable and controlled communication between neurons. One of the essential roles that the meis2 expressing cortical GABAergic cell plays in the organism is in establishing a balance between excitation and inhibition in neuronal signaling. The primary neurotransmitter that this cell synthesizes and releases is GABA, the main inhibitory neurotransmitter in the mammalian central nervous system. It acts to reduce neuronal excitability and prevents over-firing of neurons, effectively preventing excessive neuronal activity that could lead to seizures or overstimulation. By countering excessive excitatory signals, GABAergic cells work to stabilize the intricate dynamics of the brain and maintain physiological homeostasis. (This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.) A GABAergic cell located in the cerebral cortex that expresses meis2. https://cellxgene.cziscience.com/cellguide/CL_4023065 meis2 GABA homeobox protein Meis2