part of part of has part has characteristic directly develops from columnar/cuboidal epithelial cell respiratory tract epithelial cell multiciliated epithelial cell respiratory tract multiciliated cell 2023-01-25T11:06:01Z respiratory ciliated cell Respiratory ciliated cells, also known as ciliated columnar epithelial cells, are a distinct cell type primarily lining the respiratory tract. They have a columnar shape and hair-like cilia on their surface, and can be found in the trachea, bronchi, and bronchioles The main function of respiratory ciliated cells is to facilitate the movement of mucus along the respiratory tract. Goblet cells produce mucus containing trapped particles, and the coordinated motion of the cilia propels this mucus upward and away from the lungs. This process, known as mucociliary clearance, maintains respiratory hygiene and safeguards the lungs from infections. Beyond mucociliary clearance, respiratory ciliated cells also contribute to sensing and responding to the external environment. The cells possess receptors that detect chemical and mechanical stimuli, allowing the body to respond appropriately to inhaled substances or changes in breathing conditions. Recent research suggests their potential involvement in regulating the immune response during respiratory diseases, highlighting their role in immune modulation within the respiratory tract. (This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.) ciliated cell of the respiratory tract https://cellxgene.cziscience.com/cellguide/CL_4030034 respiratory multiciliated cell A multiciliated epithelial cell located in the respiratory tract epithelium, characterized by a columnar shape and motile cilia on its apical surface. This cell develops through a highly orchestrated process, transitioning from a basal progenitor via an intermediate deuterosomal cell stage that generates centrioles essential for ciliogenesis. deuterosomal cell motile cilium multiciliated respiratory tract epithelium