candelabrum cell 2024-10-15T11:06:31Z CC Candelabrum cells are the most abundant interneurons in the Purkinje cell layer and are present in all cerebellar lobules. candelabrum interneuron A GABAergic interneuron located in the Purkinje layer of the cerebellar cortex. This GABAergic interneuron type has a distinct morphology, it presents a small cell soma near the Purkinje cell layer (PCL), dendrites that extend to the surface of the molecular layer, and beaded axons that make local synapses contacts within the molecular layer. A candelabrum cell is excited by mossy fibers and granule cells but inhibited by Purkinje cells, and it inhibits molecular layer interneurons, which leads to the disinhibition of Purkinje cells. Purkinje layer interneuron