afferent neuron central nervous system neuron CGRP-expressing neuron 2024-10-30T15:35:08Z CGRP-expressing interneuron Calcitonin gene-related peptide neuron An interneuron neuron characterized by the expression of calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide. This neuron type is involved in nociception and pain modulation by facilitating the transmission of nociceptive signals from peripheral sensory nerve endings to central nervous system structures. This neuron type is found in the dorsal root ganglia (DRG) and trigeminal ganglion, and the spinal cord dorsal horn. CGRP-positive neuron