has soma location has soma location expresses expresses autonomic neuron intrinsic cardiac ganglion TH neuron 2026-03-13T11:13:54Z catecholaminergic intrinsic cardiac neuron A catecholaminergic neuron whose soma is located in an intrinsic cardiac ganglion and that expresses tyrosine hydroxylase (TH, encoded by TH), the rate-limiting enzyme in catecholamine biosynthesis. This neuron constitutes a minor subpopulation within the predominantly cholinergic parasympathetic intrinsic cardiac nervous system, identified in adult human cardiac ganglia by immunohistochemistry (Singh et al. 1999, PMID:9918529; Kawano et al. 2003, DOI:10.1007/s003800300005). It participates in local cardiac autonomic regulation, including modulation of heart rate and contractility. Its catecholaminergic phenotype distinguishes it from the majority cholinergic neurons of the same ganglia. tyrosine 3-monooxygenase cardiac ganglion