immunoglobulin complex, circulating IgE immunoglobulin complex IgE immunoglobulin complex, circulating A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:0071743 Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available. cellular_component 2010-03-24T01:44:53Z IgE antibody Ascomycota