part of part of overlaps adjacent to Mammalia hepatic acinus hepatic acinus zone 1 hepatic acinus zone 3 hepatic acinus zone 2 The region of the hepatic acinus in between zones 1 and 3. Blood in this region has an intermediate oxygen concentration relative to the other two zones of the hepatic acinus. Zone 2 is located in the midzonal region of the liver lobule. Hepatocytes in this region have mixed functionality in comparison with those in zones 1 and 3. 2020-09-08T15:15:57Z hepatic acinus intermediary zone UBERON:8400003 metabolic zone of liver liver lobule midzonal region