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    <!-- http://purl.obolibrary.org/obo/CLO_0009465 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CLO_0009465">
        <rdfs:label xml:lang="en">U-937 cell</rdfs:label>
        <rdfs:label xml:lang="zh">U-937 细胞</rdfs:label>
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    <Class rdf:about="http://purl.obolibrary.org/obo/CLO_0054340">
        <rdfs:label xml:lang="en">NICR627 cell</rdfs:label>
        <rdfs:label xml:lang="zh">NICR627 细胞</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CLO_0009465"/>
        <ns2:CLO_0051622 xml:lang="en">3131C0001000700059</ns2:CLO_0051622>
        <ns2:CLO_0037192 xml:lang="en">Amelogenin:X；CSF1PO:12；D13S317:10,12；D16S539:12；D18S51:13,14；D19S433:14,16；D21S11:27,29；D2S1338:17,20；D3S1358:16；D5S818:12；D7S820:9,11；D8S1179:12,13；FGA:22,25；TH01:6,9.3；TPOX:8,11；vWA:14,15</ns2:CLO_0037192>
        <ns2:CLO_0051629 xml:lang="en">Base Medium+8%DMSO+20%FBS</ns2:CLO_0051629>
        <ns2:CLO_0051636 xml:lang="en">Cell Resource Center of Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences</ns2:CLO_0051636>
        <ns2:CLO_0051633 xml:lang="en">Class B</ns2:CLO_0051633>
        <ns2:CLO_0051637 xml:lang="en">Contacts: Songhua Chen: Cell Resources Center, Shanghai Institute of life sciences, Chinese Academy of Sciences, zip code: 200032 address: No. 320, Yueyang Road, Shanghai, 021-54920404021-54920405: Fax: 021-54920612 Email: shchen@sibs.ac.cn.</ns2:CLO_0051637>
        <ns2:CLO_0051623 xml:lang="en">Human Histiocytic Lymphoma Cells; U937 [U-937]</ns2:CLO_0051623>
        <ns2:IAO_0000118 xml:lang="en">NICR627</ns2:IAO_0000118>
        <ns2:CLO_0051630 xml:lang="en">Negative</ns2:CLO_0051630>
        <ns2:CLO_0051628 xml:lang="en">PN</ns2:CLO_0051628>
        <rdfs:comment xml:lang="en">The cell line (strain) of the library for research purposes only, may not be used for other purposes without permission. Users may not transfer the library cell line (strain) to a third party. Users in the publication of research papers or results, should indicate the source of cell lines (strains).</rdfs:comment>
        <ns2:CLO_0051626 xml:lang="en">The cells were isolated from the chest water of a 37-year-old white male with malignant histiocytic lymphoma by Nilsson K Laboratory in 1974. Studies since 1979 have shown that the cells can differentiate into terminal monocytes under the induction of human mixed lymphocyte culture supernatant, phorbol ester, Vit D3, γ-IFN, TNF and retinoic acid. This cell does not synthesize immunoglobulin, and is EBV-negative, and can produce lysozyme, β-2-microglobulin, and TNF-α after PMA stimulation, and express C3R, and can be used as a transfected host, and express Fas, with sensitivity to TNF and anti-Fas antibody.</ns2:CLO_0051626>
        <ns2:IAO_0000118 xml:lang="en">U-937</ns2:IAO_0000118>
        <ns2:IAO_0000118 xml:lang="en">U-937 cell</ns2:IAO_0000118>
        <ns2:CLO_0051635 xml:lang="en">U-937-cell morphology-SHCRC</ns2:CLO_0051635>
        <ns2:IAO_0000118 xml:lang="en">U937</ns2:IAO_0000118>
        <ns2:IAO_0000118 xml:lang="en">U937 cell</ns2:IAO_0000118>
        <rdfs:seeAlso xml:lang="en">http://www.cellresource.cn/fdetail.aspx?id=627</rdfs:seeAlso>
        <ns2:CLO_0051624 xml:lang="en">monocyte</ns2:CLO_0051624>
        <ns2:CLO_0051625 xml:lang="en">suspension growth</ns2:CLO_0051625>
        <ns2:CLO_0037192 xml:lang="zh">Amelogenin:X；CSF1PO:12；D13S317:10,12；D16S539:12；D18S51:13,14；D19S433:14,16；D21S11:27,29；D2S1338:17,20；D3S1358:16；D5S818:12；D7S820:9,11；D8S1179:12,13；FGA:22,25；TH01:6,9.3；TPOX:8,11；vWA:14,15</ns2:CLO_0037192>
        <ns2:CLO_0051633 xml:lang="zh">B类</ns2:CLO_0051633>
        <ns2:CLO_0051628 xml:lang="zh">PN</ns2:CLO_0051628>
        <ns2:IAO_0000118 xml:lang="zh">U-937 细胞</ns2:IAO_0000118>
        <ns2:CLO_0051635 xml:lang="zh">U-937-细胞形态-SHCRC</ns2:CLO_0051635>
        <ns2:IAO_0000118 xml:lang="zh">U937 细胞</ns2:IAO_0000118>
        <ns2:CLO_0051636 xml:lang="zh">中国科学院上海生命科学研究院细胞资源中心</ns2:CLO_0051636>
        <ns2:CLO_0051623 xml:lang="zh">人组织细胞淋巴瘤细胞；U937 [U-937]</ns2:CLO_0051623>
        <ns2:CLO_0051624 xml:lang="zh">单核细胞</ns2:CLO_0051624>
        <ns2:CLO_0051629 xml:lang="zh">基础培养基+8%DMSO+20%FBS</ns2:CLO_0051629>
        <ns2:CLO_0051625 xml:lang="zh">悬浮生长</ns2:CLO_0051625>
        <rdfs:comment xml:lang="zh">本库的细胞系(株)仅用于研究工作，未经许可不得用于其它目的。使用者不得将本库细胞系(株)转让给第三者。使用者在发表研究论文或结果时，应注明细胞系(株)的来源。</rdfs:comment>
        <ns2:CLO_0051637 xml:lang="zh">联系人：陈松华 单位：中国科学院上海生命科学研究院细胞资源中心 邮编：200032 地址：上海市岳阳路320号 电话：021-54920404，021-54920405 传真：021-54920612 Email: shchen@sibs.ac.cn</ns2:CLO_0051637>
        <ns2:CLO_0051626 xml:lang="zh">该细胞是由Nilsson K实验室于1974年从一名37岁的患有恶性组织细胞性淋巴瘤的白人男性的胸水中分离建立的。1979年来的研究显示该细胞在人混合淋巴细胞培养物上清、佛波酯、Vit D3、γ-IFN、TNF和维A酸的诱导下可以向终末单核细胞分化。该细胞不合成免疫球蛋白，EBV阴性；可产生溶菌酶、β-2-微球蛋白，受PMA刺激后可产生TNF-α；表达C3R；可作转染宿主；表达Fas，对TNF和抗Fas的抗体敏感。</ns2:CLO_0051626>
        <ns2:CLO_0051630 xml:lang="zh">阴性</ns2:CLO_0051630>
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