<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/CLO-NICR?iri=http://purl.obolibrary.org/obo/CL_0000057"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000118"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0002202 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002202">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label xml:lang="en">develops from</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CL_0000057 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000057">
        <rdfs:label xml:lang="en">fibroblast</rdfs:label>
        <rdfs:label xml:lang="zh">成纤维细胞</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0002320"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002202"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000134"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:comment xml:lang="en">A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.</rdfs:comment>
        <ns3:IAO_0000115 xml:lang="en">A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.</ns3:IAO_0000115>
        <rdfs:comment xml:lang="en">A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms.</rdfs:comment>
        <rdfs:comment xml:lang="en">A large, flat, oval cell found in connective tissue and responsible for the formation of fibers.</rdfs:comment>
        <oboInOwl:hasDbXref xml:lang="en">BTO:0000452</oboInOwl:hasDbXref>
        <ns3:IAO_0000119 xml:lang="en">BTO:0000452</ns3:IAO_0000119>
        <oboInOwl:hasDbXref xml:lang="en">CALOHA:TS-0362</oboInOwl:hasDbXref>
        <ns3:IAO_0000119 xml:lang="en">CL:0000057</ns3:IAO_0000119>
        <rdfs:seeAlso xml:lang="en">EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000496</rdfs:seeAlso>
        <oboInOwl:hasDbXref xml:lang="en">FMA:63877</oboInOwl:hasDbXref>
        <ns3:IAO_0000117 xml:lang="en">James Malone</ns3:IAO_0000117>
        <ns3:IAO_0000119 xml:lang="en">NIFSTD:nlx_cell_20090201</ns3:IAO_0000119>
        <rdfs:comment xml:lang="en">These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.</rdfs:comment>
        <ns3:IAO_0000117 xml:lang="en">Tomasz Adamusiak</ns3:IAO_0000117>
        <rdfs:seeAlso xml:lang="en">URI: http://www.ebi.ac.uk/cellline#fibroblast</rdfs:seeAlso>
        <oboInOwl:hasDbXref xml:lang="en">VHOG:0001482</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace xml:lang="en">cell</oboInOwl:hasOBONamespace>
        <ns3:IAO_0000118 xml:lang="en">mouse embryonic fibroblast</ns3:IAO_0000118>
        <ns3:IAO_0000118 xml:lang="en">primary dermal fibroblast</ns3:IAO_0000118>
        <rdfs:comment xml:lang="zh">分泌富含胶原和其他大分子的细胞外基质的结缔组织细胞。</rdfs:comment>
        <ns3:IAO_0000115 xml:lang="zh">分泌富含胶原和其他大分子的细胞外基质的结缔组织细胞。有分支过程的轮廓扁平，不规则；呈梭形或纺锤形。</ns3:IAO_0000115>
        <ns3:IAO_0000118 xml:lang="zh">原发性真皮成纤维细胞</ns3:IAO_0000118>
        <rdfs:comment xml:lang="zh">在结缔组织中发现的大而扁平的椭圆形细胞，负责纤维的形成。</rdfs:comment>
        <ns3:IAO_0000118 xml:lang="zh">小鼠胚胎成纤维细胞</ns3:IAO_0000118>
        <oboInOwl:hasOBONamespace xml:lang="zh">细胞</oboInOwl:hasOBONamespace>
        <rdfs:comment xml:lang="zh">这些细胞可以是波形蛋白阳性，纤连蛋白阳性，fsp1阳性，MMP-1阳性，胶原I阳性，胶原III阳性和α-SMA阴性。</rdfs:comment>
        <rdfs:comment xml:lang="zh">间充质来源的结缔组织细胞，分泌蛋白质，尤其是分子胶原蛋白，结缔组织的细胞外纤维状基质由其形成。</rdfs:comment>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/clo.owl"/>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000134 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000134">
        <rdfs:label xml:lang="en">mesenchymal stem cell</rdfs:label>
        <rdfs:label xml:lang="zh">间充质干细胞</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0002320 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0002320">
        <rdfs:label xml:lang="en">connective tissue cell</rdfs:label>
        <rdfs:label xml:lang="zh">结缔组织细胞</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



