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    <!-- http://purl.obolibrary.org/obo/RO_0002104 -->

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        <rdfs:label xml:lang="en">has plasma membrane part</rdfs:label>
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        <rdfs:label xml:lang="en">capable of</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CL_0000048 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000048">
        <rdfs:label xml:lang="en">multi fate stem cell</rdfs:label>
        <rdfs:label xml:lang="zh">多能造血干细胞</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000134 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000134">
        <rdfs:label xml:lang="en">mesenchymal stem cell</rdfs:label>
        <rdfs:label xml:lang="zh">间充质干细胞</rdfs:label>
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            <Restriction>
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        <rdfs:subClassOf>
            <Restriction>
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        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002215"/>
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        <ns3:IAO_0000115 xml:lang="en">A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.</ns3:IAO_0000115>
        <oboInOwl:hasNarrowSynonym xml:lang="en">BMSC</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref xml:lang="en">BTO:0002625</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref xml:lang="en">BTO:0003298</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym xml:lang="en">CFU-F</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasAlternativeId xml:lang="en">CL:0002452</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref xml:lang="en">FMA:70546</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym xml:lang="en">MSC</oboInOwl:hasRelatedSynonym>
        <rdfs:comment xml:lang="en">Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2.</rdfs:comment>
        <oboInOwl:hasNarrowSynonym xml:lang="en">bone marrow stromal cells</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace xml:lang="en">cell</oboInOwl:hasOBONamespace>
        <oboInOwl:hasNarrowSynonym xml:lang="en">colony-forming unit-fibroblast</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym xml:lang="en">marrow stromal cells</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="en">mesenchymal precursor cell</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="en">mesenchymal progenitor cells</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="en">mesenchymal stem cell</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="en">mesenchymal stromal cell</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="en">mesenchymal stromal cells</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="en">stem cells, mesenchymal</oboInOwl:hasRelatedSynonym>
        <ns3:IAO_0000115 xml:lang="zh">一种结缔组织细胞，通常会产生被组织为三维团块的其他细胞。这种细胞类型是CD73阳性，CD90阳性，CD105阳性，CD45阴性，CD34阴性和MHCII阴性。它们可以在体外进一步分化成成骨细胞，脂肪细胞，肌细胞，神经元或成软骨细胞。最初被描述为居于骨髓，现在已知这种细胞类型存在于许多（如果不是全部的话）成人器官中。</ns3:IAO_0000115>
        <oboInOwl:hasRelatedSynonym xml:lang="zh">干细胞，间充质</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasOBONamespace xml:lang="zh">细胞</oboInOwl:hasOBONamespace>
        <rdfs:comment xml:lang="zh">许多但不是所有的间充质细胞都来源于中胚层。据报道，MSC为CD3阴性、CD4阴性、CD5阴性、CD8阴性、CD11a阴性、CD11b阴性、CD14阴性、CD19阴性、CD29阳性、CD31阴性、CD34阴性、CD38阴性、CD40阴性、CD44阳性、CD45阴性、CD49阳性、CD54阳性、CD66b阴性、CD79a阴性、CD80阴性、CD102阳性、CD106阳性、CD117阳性、CD121a阳性、CD121b阳性、CD123阳性、CD124阳性、CD133阴性、CD146阳性、CD166阳性、CD271阳性、B220阴性、Gr1阴性、MHCI阳性、MHCII阴性、SSEA4阴性、sca1阳性、Ter119阴性和血型糖蛋白A阴性。培养的MSC能够产生干细胞因子IL7，IL8，IL11，TGF-β，丝切蛋白，半乳糖凝集素-1，层粘连蛋白受体1，亲环蛋白A和MMP-2。</rdfs:comment>
        <oboInOwl:hasRelatedSynonym xml:lang="zh">间充质前体细胞</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="zh">间充质基质细胞(mesenchymal stromal cell)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="zh">间充质基质细胞(mesenchymal stromal cells)</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="zh">间充质干细胞</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym xml:lang="zh">间充质祖细胞</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasNarrowSynonym xml:lang="zh">集落形成单位 - 成纤维细胞</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym xml:lang="zh">骨髓基质细胞(bone marrow stromal cells)</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasNarrowSynonym xml:lang="zh">骨髓基质细胞(marrow stromal cells)</oboInOwl:hasNarrowSynonym>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/clo.owl"/>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/uberon.owl"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000219 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000219">
        <rdfs:label xml:lang="en">motile cell</rdfs:label>
        <rdfs:label xml:lang="zh">游动细胞</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0002320 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0002320">
        <rdfs:label xml:lang="en">connective tissue cell</rdfs:label>
        <rdfs:label xml:lang="zh">结缔组织细胞</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0001649 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0001649">
        <rdfs:label xml:lang="en">osteoblast differentiation</rdfs:label>
        <rdfs:label xml:lang="zh">成骨细胞分化</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0016477 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0016477">
        <rdfs:label xml:lang="en">cell migration</rdfs:label>
        <rdfs:label xml:lang="zh">细胞迁移</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0030182 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0030182">
        <rdfs:label xml:lang="en">neuron differentiation</rdfs:label>
        <rdfs:label xml:lang="zh">神经元分化</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0030855 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0030855">
        <rdfs:label xml:lang="en">epithelial cell differentiation</rdfs:label>
        <rdfs:label xml:lang="zh">上皮细胞分化</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0042613 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0042613">
        <rdfs:label xml:lang="en">MHC class II protein complex</rdfs:label>
        <rdfs:label xml:lang="zh">MHCⅡ类蛋白复合物</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0045444 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0045444">
        <rdfs:label xml:lang="en">fat cell differentiation</rdfs:label>
        <rdfs:label xml:lang="zh">脂肪细胞分化</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0055007 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0055007">
        <rdfs:label xml:lang="en">cardiac muscle cell differentiation</rdfs:label>
        <rdfs:label xml:lang="zh">心肌细胞分化</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0060591 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0060591">
        <rdfs:label xml:lang="en">chondroblast differentiation</rdfs:label>
        <rdfs:label xml:lang="zh">成软骨细胞分化</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001003 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000001003">
        <rdfs:label xml:lang="en">CD34 molecule</rdfs:label>
        <rdfs:label xml:lang="zh">CD34 分子</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001006 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000001006">
        <rdfs:label xml:lang="en">receptor-type tyrosine-protein phosphatase C</rdfs:label>
        <rdfs:label xml:lang="zh">受体型酪氨酸蛋白磷酸酶C</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001345 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000001345">
        <rdfs:label xml:lang="en">endoglin</rdfs:label>
        <rdfs:label xml:lang="zh">内皮糖蛋白</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001800 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000001800">
        <rdfs:label xml:lang="en">5&#39;-nucleotidase</rdfs:label>
        <rdfs:label xml:lang="zh">5&#39;-核苷酸酶</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001843 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000001843">
        <rdfs:label xml:lang="en">Thy-1 membrane glycoprotein</rdfs:label>
        <rdfs:label xml:lang="zh">Thy-1膜糖蛋白</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



