has part has_part participates in develops from common lymphoid progenitor 淋巴样祖细胞 pro-B cell 祖B细胞 A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs. BTO:0003104 Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative. cell pre-B cell (Philadelphia nomenclature) pre-pro B cell pro-B lymphocyte pro-B-cell pro-B-lymphocyte progenitor B cell progenitor B lymphocyte progenitor B-cell progenitor B-lymphocyte B细胞谱系的祖细胞，具有某些谱系特异性活性，如B细胞受体基因重组的早期阶段，但尚未完全变成B细胞谱系，直至发生PAX5的表达。 前B细胞（费城命名法） 前祖B细胞 据报道，人祖B细胞是CD10阳性、CD22阳性、CD34阳性、CD38阳性、CD45低、CD48阳性、CD79a阳性、CD127阳性、CD184阳性、RAG阳性、TdT阳性、Vpre-B阳性、BCR前阴性、IgD阴性和IgM阴性。转录因子表达：Pax5阳性、EBF阳性、E2A阴性、Ikaros阴性和PU.1阴性。 祖B淋巴细胞(pro-B lymphocyte) 祖B淋巴细胞(pro-B-lymphocyte) 祖B淋巴细胞(progenitor B lymphocyte) 祖B淋巴细胞(progenitor B-lymphocyte) 祖B细胞(pro-B-cell) 祖B细胞(progenitor B cell) 祖B细胞(progenitor B-cell) 细胞 lymphoid lineage restricted progenitor cell 淋巴谱系限制祖细胞 immunoglobulin V(D)J recombination 免疫球蛋白 V(D)J 重组 paired box protein PAX-5 配对盒蛋白PAX-5 DNA nucleotidylexotransferase DNA末端核苷酸转移酶