<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/CLO?iri=http://purl.obolibrary.org/obo/CL_0000792"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:cl="http://purl.obolibrary.org/obo/cl#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0002104 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002104">
        <rdfs:label xml:lang="en">has plasma membrane part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002215 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002215">
        <rdfs:label>capable of</rdfs:label>
        <rdfs:label xml:lang="en">capable of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/cl#has_low_plasma_membrane_amount -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/cl#has_low_plasma_membrane_amount">
        <rdfs:label>has_low_plasma_membrane_amount</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CL_0000624 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000624">
        <rdfs:label>CD4-positive, alpha-beta T cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000792 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000792">
        <rdfs:label>CD4-positive, CD25-positive, alpha-beta regulatory T cell</rdfs:label>
        <equivalentClass>
            <Class>
                <intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000624"/>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002104"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000001380"/>
                    </Restriction>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002215"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0050777"/>
                    </Restriction>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/cl#has_low_plasma_membrane_amount"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000001869"/>
                    </Restriction>
                </intersectionOf>
            </Class>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000624"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000815"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/cl#has_low_plasma_membrane_amount"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000001869"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002104"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PR_000001380"/>
            </Restriction>
        </rdfs:subClassOf>
        <oboInOwl:hasBroadSynonym>suppressor T lymphocyte</oboInOwl:hasBroadSynonym>
        <ns3:IAO_0000115>A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>CD4-positive, CD25-positive, alpha-beta regulatory T-cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasBroadSynonym>suppressor T cell</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasExactSynonym>CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte</oboInOwl:hasExactSynonym>
        <rdfs:comment>This cell type is compatible with the HIPC Lyoplate markers for &#39;Treg&#39;.  The inclusion of CD127lo in the logical definition is compatible with both human and mouse T cells of this subtype.</rdfs:comment>
        <oboInOwl:hasBroadSynonym>suppressor T-lymphocyte</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>Treg</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>suppressor T-cell</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasExactSynonym>CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace>cell</oboInOwl:hasOBONamespace>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000815 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000815">
        <rdfs:label>regulatory T cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/GO_0050777 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0050777">
        <rdfs:label>negative regulation of immune response</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001380 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000001380">
        <rdfs:label>interleukin-2 receptor subunit alpha</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000001869 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000001869">
        <rdfs:label>interleukin-7 receptor subunit alpha</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



