DNA ligase IV deficiency URI: http://www.ebi.ac.uk/cellline#DNA_ligase_IV_deficiency "A combined T cell and B cell immunodeficiency that is caused by a mutatino in the LIG4 gene, a DNA ligase, encoding a protein essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). Patients present with immunodeficiency and developmental and growth delay." [url:http\://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606593, url\]:http\://www.ncbi.nlm.nih.gov/gene/3981?] "LIG4 Syndrome" EXACT [] combined T cell and B cell immunodeficiency