autosomal recessive disease sickle cell anemia ICD10CM:D57.1 UMLS_CUI:C0002895 DOID:13024 SNOMEDCT_US_2025_09_01:154798006 MESH:D000755 A sickle cell disease that is characterized by the replacement of both of the beta-globin subunits in hemoglobin with hemoglobin S, resulting in a low number of red blood cells, repeated infections, and periodic episodes of pain. DOID:12924 DOID:10923 ICD9CM:282.6 disease_ontology Hb SC disease Hb-SS disease without crisis HbSS disease ORDO:232 NCI:C34383 Hb-S/Hb-C disease Hemoglobin S disease without crisis OMIM mapping confirmed by DO. [LS]. Sickle-cell/Hb-C disease without crisis drepanocytosis haemoglobin SC disease hemoglobin SC disease homozygous sickle cell disease sickle cell anaemia anemia