brain spike-and-wave discharge measurement brain spike-and-wave discharge amplitude 2013-07-30T16:41:41Z CMO:0001741 JSmith Measurement of the maximum deviation from the baseline position of the electrical signal during a series of regular, symmetrical, generalized abnormal electrical discharges in the brain, the portion of the central nervous system enclosed within the cranium which is composed of gray matter and white matter and is the primary center for the regulation and control of bodily activities, receiving and interpreting sensory impulses, and transmitting information to the muscles and body organs. Such deviations can be either positive or negative, i.e. amplitude is the distance from rest (baseline) to crest or from the rest position to the trough position. VT:0010557 brain SWD amplitude brain spike-wave activity amplitude brain spike-wave discharge amplitude clinical_measurement_ontology