calculated pancreatic islet area ratio of insulin-positive cell area to total area of splenic region of pancreas 2013-10-04T16:54:04Z A calculated measurement in which the value representing the two-dimensional extent of the part(s) of the tail region of the pancreas (that is, the portion of the pancreas which lies furthest from the major pancreatic duct and closest to the spleen, the highly vascular lymphoid organ which serves to store blood, disintegrate old blood cells, filter foreign substances from the blood, and produce lymphocytes) in which insulin, the major, fuel-regulating peptide hormone that promotes storage of glucose and inhibits lipolysis and gluconeogenesis, can be detected is divided by the value representing the entirety of the two-dimensional extent of the tail region of the pancreas, and presented as a ratio, fraction, quotient or percentage. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. CMO:0001814 VT:0005217 clinical_measurement_ontology jsmith ratio of IPCA to total area of pancreas tail region ratio of IPCA to total area of splenic region of pancreas ratio of insulin-positive cell area to total area of tail region of pancreas ratio of splenic IPCA