colonic aganglionosis severity measurement calculated colonic aganglionosis severity measurement 2013-10-15T18:10:26Z Any measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the degree to which the presentation of colonic aganglionosis has caused pain or damage, established lesions, and/or interfered with the normal functioning of the colon, the segment of the large intestine between the cecum and the rectum. Colonic aganglionosis is the absence of parasympathetic ganglion cells in any or all of the myenteric plexus, a network of autonomic nerve fibers within the tunica muscularis of the wall of the alimentary canal in general and of the colon in particular. CMO:0001835 JSmith MESH:D006627 calculated Hirschsprung disease severity measurement calculated intestinal aganglionosis severity measurement clinical_measurement_ontology