calculated blood CD8 cell count blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio 2013-12-03T11:30:34Z A calculated measurement in which the number of lymphocytes expressing both a relatively high amount of surface CD45RC antigen and surface CD8 antigen is divided by the number of lymphocytes expressing both a relatively low amount of surface CD45RC antigen and surface CD8 antigen, and presented as a ratio, fraction, quotient or percentage. CD45RC, also known as the leukocyte common antigen, is the protein produced by the PTPRC (protein tyrosine phosphatase, receptor type, C) gene and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. CMO:0001990 JSmith VT:0008077 blood CD45RChigh CD8 T cell count to CD45RClow CD8 T cell count ratio clinical_measurement_ontology